Glucose-Dependent Insulin Secretion from β Cell Spheroids Is Enhanced by Embedding into Softer Alginate Hydrogels Functionalised with RGD Peptide

Type 1 diabetes results from the loss of pancreatic β cells, reduced insulin secretion and dysregulated blood glucose levels. Replacement of these lost β cells with stem cell-derived β cells, and protecting these cells within macro-device implants is a promising approach to restore glucose homeostas...

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Detalles Bibliográficos
Autores principales: Amin, Md Lutful, Deng, Kylie, Tran, Hien A., Singh, Reena, Rnjak-Kovacina, Jelena, Thorn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774350/
https://www.ncbi.nlm.nih.gov/pubmed/36550929
http://dx.doi.org/10.3390/bioengineering9120722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774350/
https://www.ncbi.nlm.nih.gov/pubmed/36550929
http://dx.doi.org/10.3390/bioengineering9120722

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