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Structural Evaluation and Conformational Dynamics of ZNF141(T474I) Mutation Provoking Postaxial Polydactyly Type A

Postaxial Polydactyly (PAP) is a congenital disorder of limb abnormalities characterized by posterior extra digits. Mutations in the N-terminal region of the Zinc finger protein 141 (ZNF141) gene were recently linked with PAP type A. Zinc finger proteins exhibit similarity at their N-terminal region...

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Detalles Bibliográficos
Autores principales: Ali, Yasir, Ahmad, Faisal, Ullah, Muhammad Farhat, Haq, Noor Ul, Haq, M. Inam Ul, Aziz, Abdul, Zouidi, Ferjeni, Khan, M. Ijaz, Eldin, Sayed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774408/
https://www.ncbi.nlm.nih.gov/pubmed/36550955
http://dx.doi.org/10.3390/bioengineering9120749