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Peroxisome Proliferator-Activated Receptor α Attenuates Hypertensive Vascular Remodeling by Protecting Vascular Smooth Muscle Cells from Angiotensin II-Induced ROS Production

Vascular remodeling is the fundamental basis for hypertensive disease, in which vascular smooth muscle cell (VSMC) dysfunction plays an essential role. Previous studies suggest that the activation of peroxisome proliferator-activated receptor α (PPARα) by fibrate drugs has cardiovascular benefits in...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Duan, Yan, Zhao, Nan, Zhu, Xinxin, Yu, Xiaoting, Jiao, Shiyu, Song, Yanting, Shi, Li, Ma, Yutao, Wang, Xia, Yu, Baoqi, Qu, Aijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774484/
https://www.ncbi.nlm.nih.gov/pubmed/36552585
http://dx.doi.org/10.3390/antiox11122378