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Membrane Lipid Reshaping Underlies Oxidative Stress Sensing by the Mitochondrial Proteins UCP1 and ANT1

Oxidative stress and ROS are important players in the pathogenesis of numerous diseases. In addition to directly altering proteins, ROS also affects lipids with negative intrinsic curvature such as phosphatidylethanolamine (PE), producing PE adducts and lysolipids. The formation of PE adducts potent...

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Detalles Bibliográficos
Autores principales: Jovanović, Olga, Chekashkina, Ksenia, Škulj, Sanja, Žuna, Kristina, Vazdar, Mario, Bashkirov, Pavel V., Pohl, Elena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774536/
https://www.ncbi.nlm.nih.gov/pubmed/36552523
http://dx.doi.org/10.3390/antiox11122314