Metabolic Rewiring toward Oxidative Phosphorylation Disrupts Intrinsic Resistance to Ferroptosis of the Colon Adenocarcinoma Cells

Glutathione peroxidase 4 (GPX4) has been reported as one of the major targets for ferroptosis induction, due to its pivotal role in lipid hydroperoxide removal. However, recent studies pointed toward alternative antioxidant systems in this context, such as the Coenzyme Q-FSP1 pathway. To investigate...

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Detalles Bibliográficos
Autores principales: Gotorbe, Célia, Durivault, Jérôme, Meira, Willian, Cassim, Shamir, Ždralević, Maša, Pouysségur, Jacques, Vučetić, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774558/
https://www.ncbi.nlm.nih.gov/pubmed/36552620
http://dx.doi.org/10.3390/antiox11122412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774558/
https://www.ncbi.nlm.nih.gov/pubmed/36552620
http://dx.doi.org/10.3390/antiox11122412

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