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Evaluation of a Sequential Antibiotic Treatment Regimen of Ampicillin, Ciprofloxacin and Fosfomycin against Escherichia coli CFT073 in the Hollow Fiber Infection Model Compared with Simultaneous Combination Treatment

Objective: Employ the hollow fiber infection model (HFIM) to study sequential antibiotic administration (ampicillin, ciprofloxacin and fosfomycin) using human pharmacokinetic profiles to measure changes in the rate of antibiotic resistance development and compare this to simultaneous combination the...

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Detalles Bibliográficos
Autores principales: Krishna, Ashok, Zere, Tesfalem, Mistry, Sabyasachy, Ismaiel, Omnia, Stone, Heather, Sacks, Leonard V., Weaver, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774593/
https://www.ncbi.nlm.nih.gov/pubmed/36551362
http://dx.doi.org/10.3390/antibiotics11121705