β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study

Background: Autophagy can confer protection to pancreatic β-cells from the harmful effects of metabolic stress by delaying apoptosis. Curcumin (CUR) alleviates oxidative and endoplasmic reticulum (ER) stress, activates autophagy, reduces inflammation, and decreases β-cell damage in type I diabetes....

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Detalles Bibliográficos
Autores principales: Khater, Safaa I., Dowidar, Mohamed F., Abdel-Aziz, Aya E., Khamis, Tarek, Dahran, Naief, Alqahtani, Leena S., Metwally, Mohamed M. M., Al-Hady Abd-Elrahamn, Al-Sayed, Alsieni, Mohammed, Alosaimi, Manal E., Abduljabbar, Maram H., Mohamed, Amany Abdel-Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774820/
https://www.ncbi.nlm.nih.gov/pubmed/36552609
http://dx.doi.org/10.3390/antiox11122400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774820/
https://www.ncbi.nlm.nih.gov/pubmed/36552609
http://dx.doi.org/10.3390/antiox11122400

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