Cargando…

β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study

Background: Autophagy can confer protection to pancreatic β-cells from the harmful effects of metabolic stress by delaying apoptosis. Curcumin (CUR) alleviates oxidative and endoplasmic reticulum (ER) stress, activates autophagy, reduces inflammation, and decreases β-cell damage in type I diabetes....

Descripción completa

Detalles Bibliográficos
Autores principales:	Khater, Safaa I., Dowidar, Mohamed F., Abdel-Aziz, Aya E., Khamis, Tarek, Dahran, Naief, Alqahtani, Leena S., Metwally, Mohamed M. M., Al-Hady Abd-Elrahamn, Al-Sayed, Alsieni, Mohammed, Alosaimi, Manal E., Abduljabbar, Maram H., Mohamed, Amany Abdel-Rahman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774820/ https://www.ncbi.nlm.nih.gov/pubmed/36552609 http://dx.doi.org/10.3390/antiox11122400

Ejemplares similares

Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring
por: Khater, Safaa I., et al.
Publicado: (2023)

Concerns with Male Infertility Induced by Exposure to Titanium Nanoparticles and the Supporting Impact of Pelargonium graveolens Essential Oil: Morphometric Records in Male-Wistar Rats
por: Said, Ahmed Abdou, et al.
Publicado: (2022)

Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats
por: Abd El-Hakim, Yasmina M., et al.
Publicado: (2020)

Green Synthesized Zinc Oxide Nanoparticles Using Moringa olifera Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats
por: Mostafa-Hedeab, Gomaa, et al.
Publicado: (2023)

Autophagy characteristics of phytoestrogens in management and prevention of diseases: A narrative review of in-vivo and in-vitro studies
por: Khater, Safaa I., et al.
Publicado: (2023)

The Antioxidant Role of a Taurine-Enriched Diet in Combating the Immunotoxic and Inflammatory Effects of Pyrethroids and/or Carbamates in Oreochromis niloticus
por: Abdel-Rahman Mohamed, Amany, et al.
Publicado: (2021)

Characterization and Bio-Evaluation of the Synergistic Effect of Simvastatin and Folic Acid as Wound Dressings on the Healing Process
por: Hashem, Mahmoud A., et al.
Publicado: (2023)

Cytodifferentiation of pinealocytes (I and II) and astrocyte types of mature male sheep epiphysis cerebri with special emphasis on the presence of neuronal and pigmented-like cells
por: Dahran, Naief, et al.
Publicado: (2023)

Cytodifferentiation of Wulzen's cone of mature male sheep hypophysis cerebri with special emphasis on its parenchymal correlations with the adjacent pars distalis, pars intermedia and pars nervosa
por: Dahran, Naief, et al.
Publicado: (2023)

The Effects of Bacterial Lipopolysaccharide (LPS) on Turkey Poults: Assessment of Biochemical Parameters and Histopathological Changes
por: Abou Elazab, Mohamed F., et al.
Publicado: (2022)

Patterns and barriers of mental health service utilization among medical students: a cross-sectional study
por: Abdel-Hady, Doaa, et al.
Publicado: (2022)

The length of hospital stays and clinical and therapeutic characteristics of patients with COVID-19 early in the pandemic in Taif City, KSA: A retrospective study
por: Abduljabbar, Maram, et al.
Publicado: (2022)

DNA Methylation of TGFβ Target Genes: Epigenetic Control of TGFβ Functional Duality in Liver Cancer
por: Bévant, Kevin, et al.
Publicado: (2021)

Ameliorative Effects of Bovine Lactoferrin on Benzene-Induced Hematotoxicity in Albino Rats
por: Elazab, Mohamed F. Abou, et al.
Publicado: (2022)

Evaluation of flaxseed lignan-enriched extract targeting autophagy, apoptosis, and hedgehog pathways against experimentally induced obesity
por: Khater, Safaa I., et al.
Publicado: (2023)

Dissipation and Residues of Imidacloprid and Its Efficacy against Whitefly, Bemisia tabaci, in Tomato Plants under Field Conditions
por: Abdel razik, Manal A. A., et al.
Publicado: (2022)

Use of Arc Furnace Slag and Ceramic Sludge for the Production of Lightweight and Highly Porous Ceramic Materials
por: Khater, Gamal A., et al.
Publicado: (2022)

Effect of Selenium Nanoparticles and/or Bee Venom against STZ-Induced Diabetic Cardiomyopathy and Nephropathy
por: Lotfy, Mona M., et al.
Publicado: (2023)

Lymphocyte to monocyte ratio predicts survival and is epigenetically linked to miR-222-3p and miR-26b-5p in diffuse large B cell lymphoma
por: Metwally, Ayman Mohamed, et al.
Publicado: (2023)

Prevalence of gastro-oesophageal reflux disease, and its associated risk factors among medical students: a nation-based cross-sectional study
por: Baklola, Mohamed, et al.
Publicado: (2023)

Supplementation of Lipoic Acid, Zinc and Clopidogrel Reduces Mortality Rate and Incidence of Ventricular Arrhythmia in Experimental Myocardial Infarction
por: Abdel-Hady, Enas, et al.
Publicado: (2021)

Normalized periprostatic fat MRI measurements can predict prostate cancer aggressiveness in men undergoing radical prostatectomy for clinically localised disease
por: Dahran, Naief, et al.
Publicado: (2017)

Therapeutic Potential of Quercetin Loaded Nanoparticles: Novel Insights in Alleviating Colitis in an Experimental DSS Induced Colitis Model
por: Khater, Safaa I., et al.
Publicado: (2022)

Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study
por: Fawzy, Manal S., et al.
Publicado: (2017)

Modulatory effect of dietary probiotic and prebiotic supplementation on growth, immuno-biochemical alterations, DNA damage, and pathological changes in E. coli-infected broiler chicks
por: Hashem, Mohamed A., et al.
Publicado: (2022)

Parasitological, Molecular, and Histopathological Investigation of the Potential Activity of Propolis and Wheat Germ Oil against Acute Toxoplasmosis in Mice
por: Barakat, Ashraf Mohamed, et al.
Publicado: (2023)

Disruptive behavior in Down syndrome children: a cross-sectional comparative study
por: Yahia, Sohier, et al.
Publicado: (2014)

Green Biodegradable Polylactide-Based Polyurethane Triblock Copolymers Reinforced with Cellulose Nanowhiskers
por: Khattab, Mohamed, et al.
Publicado: (2023)

Insights into HPLC-MS/MS Analysis, Antioxidant and Cytotoxic Activity of Astragalus fruticosus against Different Types of Cancer Cell Lines
por: Dekinash, Mohamed Fayez, et al.
Publicado: (2022)

Volar locking plate fixation for distal radius fractures: did variable-angle plates make difference?
por: Abdel-Wahed, Mohamed, et al.
Publicado: (2022)

Towards a better understanding of annotation tools for medical imaging: a survey
por: Aljabri, Manar, et al.
Publicado: (2022)

Hexosomes as Efficient Platforms for Possible Fluoxetine Hydrochloride Repurposing with Improved Cytotoxicity against HepG2 Cells
por: Abdel-Bar, Hend Mohamed, et al.
Publicado: (2020)

Hepatic and renal toxicity following the injection of copper oxide nanoparticles (CuO NPs) in mature male Westar rats: histochemical and caspase 3 immunohistochemical reactivities
por: Ghonimi, Wael A. M., et al.
Publicado: (2022)

Faecal calprotectin in COVID-19 patients with intestinal symptoms
por: Ellakany, Walid Ismail, et al.
Publicado: (2022)

Concomitant protective and therapeutic role of verapamil in chronic mercury induced nephrotoxicity in the adult rat: histological, morphometric and ultrastructural study
por: Haleem, Nabila Yousef Abdel, et al.
Publicado: (2015)

Passive Smoking as a Risk Factor of Dry Eye in Children
por: El-Shazly, Amany Abdel-Fattah, et al.
Publicado: (2012)

Influence of active versus passive parental presence on the behavior of preschoolers with different intelligence levels in the dental operatory: a randomized controlled clinical trial
por: AlDhelai, Thiyezen Abdullah, et al.
Publicado: (2021)

Impact of Bone Marrow Natural Killer Cells (NK); Soluble TNF-α and IL-32 Levels in Myelodysplastic Syndrome Patients
por: Aref, Salah, et al.
Publicado: (2020)

Probiotic Zado® (Ruminococcus Flavefaciens) boosts hematology, immune, serum proteins, and growth profiles in Nile tilapia (Oreochromis niloticus)
por: Gayed, Mohamed Abdel, et al.
Publicado: (2021)

Amniotic Fluid-Derived Mesenchymal Stem Cells Cut Short the Acuteness of Cisplatin-Induced Nephrotoxicity in Sprague-Dawley Rats
por: Al-Husseiny, Fatma, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_a8srs46f7lnm0uua9hpnlph1sn