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β-Lactam Dosing in Critical Patients: A Narrative Review of Optimal Efficacy and the Prevention of Resistance and Toxicity

Antimicrobial prescription in critically ill patients represents a complex challenge due to the difficult balance between infection treatment and toxicity prevention. Underexposure to antibiotics and therapeutic failure or, conversely, drug overexposure and toxicity may both contribute to a worse pr...

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Detalles Bibliográficos
Autores principales: Pereira, João Gonçalves, Fernandes, Joana, Duarte, Ana Rita, Fernandes, Susana Mendes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9774837/
https://www.ncbi.nlm.nih.gov/pubmed/36551496
http://dx.doi.org/10.3390/antibiotics11121839