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The Effects of Synthetic SREBP-1 and PPAR-γ Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation

Acne vulgaris has a pathogenesis that involves increased sebum production and perifollicular inflammation. Sterol regulatory element-binding protein-1 (SREBP-1) and peroxisome proliferator activated receptor-γ (PPAR-γ) are transcription factors that regulate numerous genes involved in lipid biosynth...

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Detalles Bibliográficos
Autores principales: Gu, Hyemin, An, Hyun-Jin, Gwon, Mi-Gyeong, Bae, Seongjae, Zouboulis, Christos C., Park, Kwan-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775059/
https://www.ncbi.nlm.nih.gov/pubmed/36551286
http://dx.doi.org/10.3390/biom12121858