Cargando…

The Effects of Synthetic SREBP-1 and PPAR-γ Decoy Oligodeoxynucleotide on Acne-like Disease In Vivo and In Vitro via Lipogenic Regulation

Acne vulgaris has a pathogenesis that involves increased sebum production and perifollicular inflammation. Sterol regulatory element-binding protein-1 (SREBP-1) and peroxisome proliferator activated receptor-γ (PPAR-γ) are transcription factors that regulate numerous genes involved in lipid biosynth...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Hyemin, An, Hyun-Jin, Gwon, Mi-Gyeong, Bae, Seongjae, Zouboulis, Christos C., Park, Kwan-Kyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775059/ https://www.ncbi.nlm.nih.gov/pubmed/36551286 http://dx.doi.org/10.3390/biom12121858

Ejemplares similares

Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia
por: An, Hyun-Jin, et al.
Publicado: (2020)

Bee Venom and Its Major Component Melittin Attenuated Cutibacterium acnes- and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway
por: Gu, Hyemin, et al.
Publicado: (2022)

The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model
por: Gwon, Mi-Gyeong, et al.
Publicado: (2023)

STAT3/NF-κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF-κB signaling pathway in a mouse model of atherosclerosis
por: An, Hyun-Jin, et al.
Publicado: (2023)

Inhibitory Effects of STAT3 Transcription Factor by Synthetic Decoy ODNs on Autophagy in Renal Fibrosis
por: Kim, Young-Ah, et al.
Publicado: (2021)

Antifibrotic Effect of Smad Decoy Oligodeoxynucleotide in a CCl(4)-Induced Hepatic Fibrosis Animal Model
por: Gwon, Mi-Gyeong, et al.
Publicado: (2018)

Anti-Fibrotic Effect of Synthetic Noncoding Oligodeoxynucleotide for Inhibiting mTOR and STAT3 via the Regulation of Autophagy in an Animal Model of Renal Injury
por: Jung, Hyun Jin, et al.
Publicado: (2022)

Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis
por: Kim, Jung-Yeon, et al.
Publicado: (2017)

Modeling the therapeutic efficacy of NFκB synthetic decoy oligodeoxynucleotides (ODNs)
por: Wang, Zhipeng, et al.
Publicado: (2018)

Synthetic Non-Coding RNA for Suppressing mTOR Translation to Prevent Renal Fibrosis Related to Autophagy in UUO Mouse Model
por: Kim, Young-Ah, et al.
Publicado: (2022)

STAT-1 decoy oligodeoxynucleotide inhibition of acute rejection in mouse heart transplants
por: Stojanovic, Tomislav, et al.
Publicado: (2009)

Biochemical Properties of a Decoy Oligodeoxynucleotide Inhibitor of STAT3 Transcription Factor
por: Lee, David S., et al.
Publicado: (2018)

Therapeutic Effect of Bee Venom and Melittin on Skin Infection Caused by Streptococcus pyogenes
por: Bae, Seongjae, et al.
Publicado: (2022)

Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
por: Zhang, Xulong, et al.
Publicado: (2007)

NF-κB Decoy Oligodeoxynucleotide-Coated Balloon Catheter for Arteriovenous Fistula in Hemodialysis
por: Fukasawa, Mizuya, et al.
Publicado: (2018)

Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice
por: He, Fei, et al.
Publicado: (2022)

Acne Syndromes and Mosaicism
por: Baroud, Sumer, et al.
Publicado: (2021)

Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2
por: Wang, Siying, et al.
Publicado: (2023)

Inhibitory short synthetic oligodeoxynucleotides and lupus
por: Liu, Zheng, et al.
Publicado: (2009)

Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1
por: Torres-Ayuso, P, et al.
Publicado: (2015)

Influence of pentylenetetrazol and NF-κB decoy oligodeoxynucleotides on p38 expression in neuron-like cells
por: YANG, JIA-JUN, et al.
Publicado: (2014)

Class C1 decoy oligodeoxynucleotide inhibits profibrotic genes expression in rat hepatic stellate cells
por: Rao, Chun, et al.
Publicado: (2020)

Magma Seawater Inhibits Hepatic Lipid Accumulation through Suppression of Lipogenic Enzymes Regulated by SREBPs in Thioacetamide-Injected Rats
por: Woo, Minji, et al.
Publicado: (2019)

mTORC2 Regulates Lipogenic Gene Expression through PPARγ to Control Lipid Synthesis in Bovine Mammary Epithelial Cells
por: Guo, Zhixin, et al.
Publicado: (2019)

The LXRB-SREBP1 network regulates lipogenic homeostasis by controlling the synthesis of polyunsaturated fatty acids in goat mammary epithelial cells
por: Zhang, Wenying, et al.
Publicado: (2022)

Inhibitory effect of ribbon-type NF-κB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo
por: Kunugiza, Yasuo, et al.
Publicado: (2006)

Suppression of chronic inflammation with engineered nanomaterials delivering nuclear factor κB transcription factor decoy oligodeoxynucleotides
por: Farahmand, Leila, et al.
Publicado: (2017)

DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer
por: Casas, Geoffrey, et al.
Publicado: (2022)

Cooperation of Oligodeoxynucleotides and Synthetic Molecules as Enhanced Immune Modulators
por: Nigar, Shireen, et al.
Publicado: (2019)

The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides
por: Chirila, Traian V, et al.
Publicado: (2002)

Anti-Fibrotic Effect of Synthetic Noncoding Decoy ODNs for TFEB in an Animal Model of Chronic Kidney Disease
por: Lee, Sun-Jae, et al.
Publicado: (2022)

Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis
por: Wee, Jee Hye, et al.
Publicado: (2017)

Ultrasound microbubble-mediated transfection of NF-κB decoy oligodeoxynucleotide into gingival tissues inhibits periodontitis in rats in vivo
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2017)

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides
por: Jiang, Hongmei, et al.
Publicado: (2017)

A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method
por: Yamaguchi, Hiroyuki, et al.
Publicado: (2017)

Protective Effects of 6-Shogaol, an Active Compound of Ginger, in a Murine Model of Cisplatin-Induced Acute Kidney Injury
por: Gwon, Mi-Gyeong, et al.
Publicado: (2021)

Acne and Stress: Impact of Catecholamines on Cutibacterium acnes
por: Borrel, Valérie, et al.
Publicado: (2019)

PPARα-dependent Insig2a overexpression inhibits SREBP-1c processing during fasting
por: Lee, Jae-Ho, et al.
Publicado: (2017)

Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs
por: Fernø, Johan, et al.
Publicado: (2006)

Involvement of G-Protein-Coupled Receptor 40 in the Inhibitory Effects of Docosahexaenoic Acid on SREBP1-Mediated Lipogenic Enzyme Expression in Primary Hepatocytes
por: On, Seungtae, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j0eokaobf5c9ei70tf0a113hbc