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Local Attraction of Substrates and Co-Substrates Enhances Weak Acid and Base Transmembrane Transport

The transmembrane transport of weak acid and base metabolites depends on the local pH conditions that affect the protonation status of the substrates and the availability of co-substrates, typically protons. Different protein designs ensure the attraction of substrates and co-substrates to the trans...

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Detalles Bibliográficos
Autores principales: Epalle, Nathan Hugo, Beitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775063/
https://www.ncbi.nlm.nih.gov/pubmed/36551222
http://dx.doi.org/10.3390/biom12121794