Changes in Alprazolam Metabolism by CYP3A43 Mutants

Alprazolam is a triazolobenzodiazepine which is most commonly used in the short-term management of anxiety disorders, often in combination with antipsychotics. The four human members of the CYP3A subfamily are mainly responsible for its metabolism, which yields the main metabolites 4-hydroxyalprazol...

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Detalles Bibliográficos
Autores principales: Zhao, Jie, Liu, Sijie, Wolf, Clemens Alexander, Wolber, Gerhard, Parr, Maria Kristina, Bureik, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775082/
https://www.ncbi.nlm.nih.gov/pubmed/36551778
http://dx.doi.org/10.3390/biomedicines10123022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775082/
https://www.ncbi.nlm.nih.gov/pubmed/36551778
http://dx.doi.org/10.3390/biomedicines10123022

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