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Advances in Gene Therapy Techniques to Treat LRRK2 Gene Mutation

Leucine-rich repeat kinase 2 (LRRK2) gene mutation is an autosomal dominant mutation associated with Parkinson’s disease (PD). Among LRRK2 gene mutations, the LRRK2 G2019S mutation is frequently involved in PD onset. Currently, diverse gene correction tools such as zinc finger nucleases (ZFNs), help...

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Detalles Bibliográficos
Autores principales: Chung, Sun-Ku, Lee, Seo-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775085/
https://www.ncbi.nlm.nih.gov/pubmed/36551242
http://dx.doi.org/10.3390/biom12121814