The Role of Membrane Affinity and Binding Modes in Alpha-Synuclein Regulation of Vesicle Release and Trafficking

Alpha-synuclein is a presynaptic protein linked to Parkinson’s disease with a poorly characterized physiological role in regulating the synaptic vesicle cycle. Using RBL-2H3 cells as a model system, we earlier reported that wild-type alpha-synuclein can act as both an inhibitor and a potentiator of...

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Detalles Bibliográficos
Autores principales: Das, Tapojyoti, Ramezani, Meraj, Snead, David, Follmer, Cristian, Chung, Peter, Lee, Ka Yee, Holowka, David A., Baird, Barbara A., Eliezer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775087/
https://www.ncbi.nlm.nih.gov/pubmed/36551244
http://dx.doi.org/10.3390/biom12121816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775087/
https://www.ncbi.nlm.nih.gov/pubmed/36551244
http://dx.doi.org/10.3390/biom12121816

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