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The Role of Membrane Affinity and Binding Modes in Alpha-Synuclein Regulation of Vesicle Release and Trafficking

Alpha-synuclein is a presynaptic protein linked to Parkinson’s disease with a poorly characterized physiological role in regulating the synaptic vesicle cycle. Using RBL-2H3 cells as a model system, we earlier reported that wild-type alpha-synuclein can act as both an inhibitor and a potentiator of...

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Detalles Bibliográficos
Autores principales:	Das, Tapojyoti, Ramezani, Meraj, Snead, David, Follmer, Cristian, Chung, Peter, Lee, Ka Yee, Holowka, David A., Baird, Barbara A., Eliezer, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775087/ https://www.ncbi.nlm.nih.gov/pubmed/36551244 http://dx.doi.org/10.3390/biom12121816

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