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Differential Regulation of MMPs, Apoptosis and Cell Proliferation by the Cannabinoid Receptors CB1 and CB2 in Vascular Smooth Muscle Cells and Cardiac Myocytes

Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB(1)R and CB(2)R. This study investigated whether cannabinoids regulate the activity of matrix metalloproteases (MMP-2, MMP-9) in vascular smooth muscle cells (VSMCs) and in cells of cardiac origin (H9c2...

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Detalles Bibliográficos
Autores principales: Greiner, Bettina, Sommerfeld, Manuela, Kintscher, Ulrich, Unger, Thomas, Kappert, Kai, Kaschina, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775096/
https://www.ncbi.nlm.nih.gov/pubmed/36552027
http://dx.doi.org/10.3390/biomedicines10123271