Cargando…
Differential Regulation of MMPs, Apoptosis and Cell Proliferation by the Cannabinoid Receptors CB1 and CB2 in Vascular Smooth Muscle Cells and Cardiac Myocytes
Cannabinoids (CB) are implicated in cardiovascular diseases via the two main receptor subtypes CB(1)R and CB(2)R. This study investigated whether cannabinoids regulate the activity of matrix metalloproteases (MMP-2, MMP-9) in vascular smooth muscle cells (VSMCs) and in cells of cardiac origin (H9c2...
Autores principales: | Greiner, Bettina, Sommerfeld, Manuela, Kintscher, Ulrich, Unger, Thomas, Kappert, Kai, Kaschina, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775096/ https://www.ncbi.nlm.nih.gov/pubmed/36552027 http://dx.doi.org/10.3390/biomedicines10123271 |
Ejemplares similares
-
Cannabigerol Action at Cannabinoid CB(1) and CB(2) Receptors and at CB(1)–CB(2) Heteroreceptor Complexes
por: Navarro, Gemma, et al.
Publicado: (2018) -
Cannabinoid CB(1) and CB(2) Receptor Signaling and Bias
por: Ibsen, Mikkel Søes, et al.
Publicado: (2017) -
Expression and Function of Cannabinoid Receptors CB1 and CB2 and Their Cognate Cannabinoid Ligands in Murine Embryonic Stem Cells
por: Jiang, Shuxian, et al.
Publicado: (2007) -
Effects of pro‐inflammatory cytokines on cannabinoid CB
(1) and CB
(2) receptors in immune cells
por: Jean‐Gilles, L., et al.
Publicado: (2015) -
Positive Allosteric Modulation of CB1 and CB2 Cannabinoid Receptors Enhances the Neuroprotective Activity of a Dual CB1R/CB2R Orthosteric Agonist
por: Polini, Beatrice, et al.
Publicado: (2020)