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A New Glutathione-Cleavable Theranostic for Photodynamic Therapy Based on Bacteriochlorin e and Styrylnaphthalimide Derivatives

Herein, we report a new conjugate BChl–S–S–NI based on the second-generation photosensitizer bacteriochlorin e6 (BChl) and a 4-styrylnaphthalimide fluorophore (NI), which is cleaved into individual functional fragments in the intracellular medium. The chromophores in the conjugate were cross-linked...

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Detalles Bibliográficos
Autores principales: Pavlova, Marina A., Panchenko, Pavel A., Alekhina, Ekaterina A., Ignatova, Anastasia A., Plyutinskaya, Anna D., Pankratov, Andrey A., Pritmov, Dmitriy A., Grin, Mikhail A., Feofanov, Alexey V., Fedorova, Olga A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775103/
https://www.ncbi.nlm.nih.gov/pubmed/36551116
http://dx.doi.org/10.3390/bios12121149