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Anti-Inflammatory Property of 5-Demethylnobiletin (5-Hydroxy-6, 7, 8, 3′, 4′-pentamethoxyflavone) and Its Metabolites in Lipopolysaccharide (LPS)-Induced RAW 264.7 Cells

SIMPLE SUMMARY: 5-Demethylnobiletin (5-hydroxy-6, 7, 8, 3′, 4′-pentamethoxyflavone, 5DN) is a bioactive polymethoxyflavone mainly found in citrus plants. To our knowledge, the present study is the first report on the inhibitory mechanism of 5DN and its metabolites on LPS-induced inflammation in RAW...

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Detalles Bibliográficos
Autores principales: Guo, Shanshan, Wu, Xian, Zheng, Jinkai, Song, Mingyue, Dong, Ping, Xiao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775120/
https://www.ncbi.nlm.nih.gov/pubmed/36552328
http://dx.doi.org/10.3390/biology11121820