Portability of a Small-Molecule Binding Site between Disordered Proteins

Intrinsically disordered proteins (IDPs) are important in both normal and disease states. Small molecules can be targeted to disordered regions, but we currently have only a limited understanding of the nature of small-molecule binding sites in IDPs. Here, we show that a minimal small-molecule bindi...

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Detalles Bibliográficos
Autores principales: Jaiprashad, Rajesh, De Silva, Sachith Roch, Fred Lucena, Lisette M., Meyer, Ella, Metallo, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775153/
https://www.ncbi.nlm.nih.gov/pubmed/36551315
http://dx.doi.org/10.3390/biom12121887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775153/
https://www.ncbi.nlm.nih.gov/pubmed/36551315
http://dx.doi.org/10.3390/biom12121887

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