NLRP3-Inflammasome Inhibition with IZD334 Does Not Reduce Cardiac Damage in a Pig Model of Myocardial Infarction

NLRP3-inflammasome-mediated signaling is thought to significantly contribute to the extent of myocardial damage after myocardial infarction (MI). The purpose of this study was to investigate the effects of the NLRP3-inflammasome inhibitor IZD334 on cardiac damage in a pig model of myocardial infarct...

Descripción completa

Detalles Bibliográficos
Autores principales: Silvis, Max J. M., Demkes, Evelyne J., Timmers, Leo, Arslan, Fatih, de Jager, Saskia C. A., Sluijter, Joost P. G., Mosterd, Arend, de Kleijn, Dominique P. V., Bosch, Lena, van Hout, Gerardus P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775177/
https://www.ncbi.nlm.nih.gov/pubmed/36551811
http://dx.doi.org/10.3390/biomedicines10123056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775177/
https://www.ncbi.nlm.nih.gov/pubmed/36551811
http://dx.doi.org/10.3390/biomedicines10123056

Ejemplares similares