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Exploring the Chemical Space of Urease Inhibitors to Extract Meaningful Trends and Drivers of Activity

[Image: see text] Blocking the catalytic activity of urease has been shown to have a key role in different diseases as well as in different agricultural applications. A vast array of molecules have been tested against ureases of different species, but the clinical translation of these compounds has...

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Detalles Bibliográficos
Autores principales: Aniceto, Natália, Bonifácio, Vasco D. B., Guedes, Rita C., Martinho, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775197/
https://www.ncbi.nlm.nih.gov/pubmed/35666858
http://dx.doi.org/10.1021/acs.jcim.2c00150