Novel Selective and Low-Toxic Inhibitor of LmCPB2.8ΔCTE (CPB) One Important Cysteine Protease for Leishmania Virulence

Leishmaniasis is a highly prevalent, yet neglected disease caused by protozoan parasites of the genus Leishmania. In the search for newer, safer, and more effective antileishmanial compounds, we herein present a study of the mode of action in addition to a detailed structural and biological characte...

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Detalles Bibliográficos
Autores principales: Moreira, Vitor Partite, da Silva Mela, Michele Ferreira, dos Anjos, Luana Ribeiro, Saraiva, Leonardo Figueiredo, Arenas Velásquez, Angela M., Kalaba, Predrag, Fabisiková, Anna, Clementino, Leandro da Costa, Aufy, Mohammed, Studenik, Christian, Gajic, Natalie, Prado-Roller, Alexander, Magalhães, Alvicler, Zehl, Martin, Figueiredo, Ingrid Delbone, Baviera, Amanda Martins, Cilli, Eduardo Maffud, Graminha, Marcia A. S., Lubec, Gert, Gonzalez, Eduardo R. Perez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775234/
https://www.ncbi.nlm.nih.gov/pubmed/36551331
http://dx.doi.org/10.3390/biom12121903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775234/
https://www.ncbi.nlm.nih.gov/pubmed/36551331
http://dx.doi.org/10.3390/biom12121903

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