Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells

Schizophrenia (SCZ) is a chronic neurodevelopmental psychotic disorder. The immune system and neuroinflammation seem to play a central role in the pathophysiology of SCZ. Clozapine is an effective atypical antipsychotic used for treatment-resistant SCZ. Life-threatening side effects, such as myocard...

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Detalles Bibliográficos
Autores principales: Yuhas, Yael, Ashkenazi, Shai, Berent, Eva, Weizman, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775287/
https://www.ncbi.nlm.nih.gov/pubmed/36552163
http://dx.doi.org/10.3390/brainsci12121703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775287/
https://www.ncbi.nlm.nih.gov/pubmed/36552163
http://dx.doi.org/10.3390/brainsci12121703

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