Cargando…

Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells

Schizophrenia (SCZ) is a chronic neurodevelopmental psychotic disorder. The immune system and neuroinflammation seem to play a central role in the pathophysiology of SCZ. Clozapine is an effective atypical antipsychotic used for treatment-resistant SCZ. Life-threatening side effects, such as myocard...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuhas, Yael, Ashkenazi, Shai, Berent, Eva, Weizman, Abraham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775287/ https://www.ncbi.nlm.nih.gov/pubmed/36552163 http://dx.doi.org/10.3390/brainsci12121703

Ejemplares similares

S41. SHORT- AND LONG-TERM OUTCOMES OF VITAMIN D SUPPLEMENTATION IN CLOZAPINE TREATED CHRONIC SCHIZOPHRENIA PATIENTS
por: Krivoy, Amir, et al.
Publicado: (2018)

Influenza A viruses suppress cyclooxygenase-2 expression by affecting its mRNA stability
por: Dudek, Sabine Eva, et al.
Publicado: (2016)

Effects of Atypical Antipsychotics, Clozapine, Quetiapine and Brexpiprazole on Astroglial Transmission Associated with Connexin43
por: Fukuyama, Kouji, et al.
Publicado: (2021)

Activation of Astroglial Connexin Is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine
por: Fukuyama, Kouji, et al.
Publicado: (2020)

Differential Serum and Urine CRP, IP-10, and TRAIL Levels in Pediatric Urinary Tract Infection
por: Ashkenazi-Hoffnung, Liat, et al.
Publicado: (2021)

Vitamin D Supplementation in Chronic Schizophrenia Patients Treated with Clozapine: A Randomized, Double-Blind, Placebo-controlled Clinical Trial
por: Krivoy, Amir, et al.
Publicado: (2017)

Mrna vaccination under clozapine treatment
por: Argitis, P., et al.
Publicado: (2022)

Detection of Interleukin-19 mRNA in C57BL/6 Mice Astroglial Cells and Brain Cortex
por: Nikfarjam, Bahareh Abd, et al.
Publicado: (2014)

Atypical astroglial pTDP‐43 pathology in astroglial predominant tauopathy
por: Gelpi, Ellen, et al.
Publicado: (2021)

Physiology of Astroglial Excitability
por: Verkhratsky, Alexei, et al.
Publicado: (2020)

Astroglial CB1 Cannabinoid Receptors Mediate CP 55,940-Induced Conditioned Place Aversion Through Cyclooxygenase-2 Signaling in Mice
por: Cong, Jin, et al.
Publicado: (2021)

Factors that contribute to faecal cyclooxygenase-2 mRNA expression in subjects with colorectal cancer
por: Hamaya, Y, et al.
Publicado: (2010)

Cyclooxygenase 1 mRNA expression is undetectable in Madin Darby Canine Kidney cells
por: Pelletier, Guillaume, et al.
Publicado: (2015)

Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures
por: Emamghoreishi, Masoumeh, et al.
Publicado: (2015)

Clozapine blood level assessment using a point-of-care device: feasibility and reliability
por: Kamhi-Nesher, Shiri, et al.
Publicado: (2022)

Astroglial Induction of in vivo Angiogenesis
por: Suárez, I., et al.
Publicado: (1994)

Astroglial Connexins in Neurodegenerative Diseases
por: Huang, Xiaomin, et al.
Publicado: (2021)

IMPACT OF COVID-19 INFECTION AND mRNA VACCINATION ON MENSTRUAL CYTOKINE PROFILES
por: Dhanani, Zainub, et al.
Publicado: (2022)

A case report: Clozapine‐induced leukopenia and neutropenia after mRNA COVID‐19 vaccination
por: Imai, Tomoyuki, et al.
Publicado: (2022)

Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species
por: Sáez, Juan C., et al.
Publicado: (2020)

β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3′-UTR
por: Lee, Hee Kyu, et al.
Publicado: (2006)

Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patients
por: Sicking, Isabel, et al.
Publicado: (2014)

Spinal astroglial cannabinoid receptors control pathological tremor
por: Carlsen, Eva Maria Meier, et al.
Publicado: (2021)

Astroglial networking contributes to neurometabolic coupling
por: Escartin, Carole, et al.
Publicado: (2013)

Hemichannels: new roles in astroglial function
por: Orellana, Juan A., et al.
Publicado: (2014)

Ammonia Affects Astroglial Proliferation in Culture
por: Bodega, Guillermo, et al.
Publicado: (2015)

RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity
por: Smith, Jayden A., et al.
Publicado: (2017)

Astroglial Glutamate Signaling and Uptake in the Hippocampus
por: Rose, Christine R., et al.
Publicado: (2018)

Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients
por: Mostaid, Md Shaki, et al.
Publicado: (2017)

Ardisia crispa roots inhibit cyclooxygenase and suppress angiogenesis
por: Awang Hamsin, Dayang Erna Zulaikha, et al.
Publicado: (2014)

Neuronal regulation of astroglial morphology and proliferation in vitro
Publicado: (1985)

Astroglial Wiring is Adding Complexity to Neuroglial Networking
por: Giaume, Christian
Publicado: (2010)

Astroglial Networks and Implications for Therapeutic Neuromodulation of Epilepsy
por: Witcher, Mark R., et al.
Publicado: (2012)

Astroglial Integrins in the Development and Regulation of Neurovascular Units
por: Tanigami, Hironobu, et al.
Publicado: (2012)

Resveratrol Prevents Ammonia Toxicity in Astroglial Cells
por: Bobermin, Larissa Daniele, et al.
Publicado: (2012)

Enhanced astroglial GABA uptake in heart failure
por: Kim, Hyun-Woo, et al.
Publicado: (2015)

Astroglial role in the pathophysiology of status epilepticus: an overview
por: Vargas-Sánchez, Karina, et al.
Publicado: (2018)

Astroglial Modulation of Hydromineral Balance and Cerebral Edema
por: Wang, Yu-Feng, et al.
Publicado: (2018)

Astroglial connexins and cognition: memory formation or deterioration?
por: He, Jin-Ting, et al.
Publicado: (2020)

Rapid recycling of glutamate transporters on the astroglial surface
por: Michaluk, Piotr, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ns2999t3h75kmvvmgqgdk1oogv