AXL-Receptor Targeted 14FN3 Based Single Domain Proteins (Pronectins™) from 3 Synthetic Human Libraries as Components for Exploring Novel Bispecific Constructs against Solid Tumors

A highly specific AXL-receptor targeted family of non-immunoglobulin, single domain protein binders (Pronectins™) have been isolated from three (3) synthetic libraries that employ the human scaffold of the 14th domain of Fibronectin III (14FN3) and evolutionary CDRs diversity of over 25 billion loop...

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Detalles Bibliográficos
Autores principales: Hokanson, Craig A., Zacco, Emanuela, Cappuccilli, Guido, Odineca, Tatjana, Crea, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775294/
https://www.ncbi.nlm.nih.gov/pubmed/36551940
http://dx.doi.org/10.3390/biomedicines10123184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775294/
https://www.ncbi.nlm.nih.gov/pubmed/36551940
http://dx.doi.org/10.3390/biomedicines10123184

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