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R-PTP-κ Inhibits Contact-Dependent Cell Growth by Suppressing E2F Activity

Density-dependent regulation of cell growth is presumed to be caused by cell-cell contact, but the underlying molecular mechanism is not yet clearly defined. Here, we report that receptor-type protein tyrosine phosphatase-kappa (R-PTP-κ) is an important regulator of cell contact-dependent growth inh...

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Detalles Bibliográficos
Autores principales: Sohn, Hyun Ahm, Kang, Minho, Ha, Hyunjung, Yeom, Young Il, Park, Kyung Chan, Lee, Dong Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775357/
https://www.ncbi.nlm.nih.gov/pubmed/36551956
http://dx.doi.org/10.3390/biomedicines10123199