Halogenation of Peptides and Proteins Using Engineered Tryptophan Halogenase Enzymes

Halogenation of bioactive peptides via incorporation of non-natural amino acid derivatives during chemical synthesis is a common strategy to enhance functionality. Bacterial tyrptophan halogenases efficiently catalyze regiospecific halogenation of the free amino acid tryptophan, both in vitro and in...

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Detalles Bibliográficos
Autores principales: Sana, Barindra, Ke, Ding, Li, Eunice Hui Yen, Ho, Timothy, Seayad, Jayasree, Duong, Hung A., Ghadessy, Farid J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775415/
https://www.ncbi.nlm.nih.gov/pubmed/36551269
http://dx.doi.org/10.3390/biom12121841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775415/
https://www.ncbi.nlm.nih.gov/pubmed/36551269
http://dx.doi.org/10.3390/biom12121841

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