The Association of CD8+ Cytotoxic T Cells and Granzyme B+ Lymphocytes with Immunosuppressive Factors, Tumor Stage and Prognosis in Cutaneous Melanoma

The immunosuppressive tumor microenvironment (TME) consists of suppressive cells producing a variety of immunomodulatory proteins, such as programmed death ligand 1 (PD-L1) and indoleamine-2,3-dioxygenase (IDO). Although granzyme B (GrB) is known to convey the cytolytic activities of CD8+ cytotoxic...

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Detalles Bibliográficos
Autores principales: Salmi, Satu, Hälinen, Kaisla, Lin, Anton, Suikkanen, Sanna, Jokelainen, Otto, Rahunen, Eija, Siiskonen, Hanna, Pasonen-Seppänen, Sanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775436/
https://www.ncbi.nlm.nih.gov/pubmed/36551965
http://dx.doi.org/10.3390/biomedicines10123209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775436/
https://www.ncbi.nlm.nih.gov/pubmed/36551965
http://dx.doi.org/10.3390/biomedicines10123209

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