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Sequence-Based Prediction of Protein Phase Separation: The Role of Beta-Pairing Propensity

The formation of droplets of bio-molecular condensates through liquid-liquid phase separation (LLPS) of their component proteins is a key factor in the maintenance of cellular homeostasis. Different protein properties were shown to be important in LLPS onset, making it possible to develop predictors...

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Detalles Bibliográficos
Autores principales: Mullick, Pratik, Trovato, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775558/
https://www.ncbi.nlm.nih.gov/pubmed/36551199
http://dx.doi.org/10.3390/biom12121771