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The Contribution of the Locus Coeruleus–Noradrenaline System Degeneration during the Progression of Alzheimer’s Disease

SIMPLE SUMMARY: Locus coeruleus degeneration occurs early in the course of Alzheimer’s disease and likely contributes to pathogenic progression. Involved mechanisms may therefore be targeted for future therapies. ABSTRACT: Alzheimer’s disease (AD), which is characterized by extracellular accumulatio...

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Detalles Bibliográficos
Autores principales: Mercan, Dilek, Heneka, Michael Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775634/
https://www.ncbi.nlm.nih.gov/pubmed/36552331
http://dx.doi.org/10.3390/biology11121822