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Conformational Dynamics of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

Variants of SARS-CoV-2 keep emerging and causing new waves of COVID-19 around the world. Effective new approaches in drug development are based on the binding of agents, such as neutralizing monoclonal antibodies to a receptor-binding domain (RBD) of SARS-CoV-2 spike protein. However, mutations in R...

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Detalles Bibliográficos
Autores principales: Mamchur, Aleksandra A., Stanishneva-Konovalova, Tatiana B., Mokrushina, Yuliana A., Abrikosova, Viktoria A., Guo, Yu, Zhang, Hongkai, Terekhov, Stanislav S., Smirnov, Ivan V., Yaroshevich, Igor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775641/
https://www.ncbi.nlm.nih.gov/pubmed/36551988
http://dx.doi.org/10.3390/biomedicines10123233