Gabapentin Increases Intra-Epidermal and Peptidergic Nerve Fibers Density and Alleviates Allodynia and Thermal Hyperalgesia in a Mouse Model of Acute Taxol-Induced Peripheral Neuropathy

The clinical pathology of Taxol-induced peripheral neuropathy (TIPN), characterized by loss of sensory sensitivity and pain, is mirrored in a preclinical pharmacological mice model in which Gabapentin, produced anti-thermal hyperalgesia and anti-allodynia effects. The study aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Klazas, Michal, Naamneh, Majdi Saleem, Zheng, Wenhua, Lazarovici, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775678/
https://www.ncbi.nlm.nih.gov/pubmed/36551946
http://dx.doi.org/10.3390/biomedicines10123190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775678/
https://www.ncbi.nlm.nih.gov/pubmed/36551946
http://dx.doi.org/10.3390/biomedicines10123190

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