Notch Missense Mutations in Drosophila Reveal Functions of Specific EGF-like Repeats in Notch Folding, Trafficking, and Signaling

Notch signaling plays various roles in cell-fate specification through direct cell–cell interactions. Notch receptors are evolutionarily conserved transmembrane proteins with multiple epidermal growth factor (EGF)-like repeats. Drosophila Notch has 36 EGF-like repeats, and while some play a role in...

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Detalles Bibliográficos
Autores principales: Nurmahdi, Hilman, Hasegawa, Mao, Mujizah, Elzava Yuslimatin, Sasamura, Takeshi, Inaki, Mikiko, Yamamoto, Shinya, Yamakawa, Tomoko, Matsuno, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775759/
https://www.ncbi.nlm.nih.gov/pubmed/36551180
http://dx.doi.org/10.3390/biom12121752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775759/
https://www.ncbi.nlm.nih.gov/pubmed/36551180
http://dx.doi.org/10.3390/biom12121752

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