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TNF Signaling Is Required for Castration-Induced Vascular Damage Preceding Prostate Cancer Regression

SIMPLE SUMMARY: Androgen deprivation therapy (ADT) is the principal therapy for advanced prostate cancer. ADT controls tumor growth by rapidly altering the prostate tumor microenvironment and subsequently inducing cancer cell death. ADT induces prostate vascular damage and thereby reduces intratumor...

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Detalles Bibliográficos
Autores principales: Krolewski, John J., Singh, Shalini, Sha, Kai, Jaiswal, Neha, Turowski, Steven G., Pan, Chunliu, Rich, Laurie J., Seshadri, Mukund, Nastiuk, Kent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775958/
https://www.ncbi.nlm.nih.gov/pubmed/36551505
http://dx.doi.org/10.3390/cancers14246020