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Phosphorylation-Mediated Activation of β-Catenin-TCF4-CEGRs/ALCDs Pathway Is an Essential Event in Development of Aggressive Hepatoblastoma

SIMPLE SUMMARY: Pediatric liver cancer hepatoblastoma has a low rate of genetic mutations, suggesting additional mechanisms that involve epigenetics and signal transduction pathways. In this paper, we present evidence showing that the phosphorylation-dependent activation of wildtype β-catenin leads...

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Detalles Bibliográficos
Autores principales: Gulati, Ruhi, Hanlon, Margaret A., Lutz, Maggie, Quitmeyer, Tyler, Geller, James, Tiao, Gregory, Timchenko, Lubov, Timchenko, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775972/
https://www.ncbi.nlm.nih.gov/pubmed/36551548
http://dx.doi.org/10.3390/cancers14246062