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Phosphorylation-Mediated Activation of β-Catenin-TCF4-CEGRs/ALCDs Pathway Is an Essential Event in Development of Aggressive Hepatoblastoma
SIMPLE SUMMARY: Pediatric liver cancer hepatoblastoma has a low rate of genetic mutations, suggesting additional mechanisms that involve epigenetics and signal transduction pathways. In this paper, we present evidence showing that the phosphorylation-dependent activation of wildtype β-catenin leads...
Autores principales: | Gulati, Ruhi, Hanlon, Margaret A., Lutz, Maggie, Quitmeyer, Tyler, Geller, James, Tiao, Gregory, Timchenko, Lubov, Timchenko, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775972/ https://www.ncbi.nlm.nih.gov/pubmed/36551548 http://dx.doi.org/10.3390/cancers14246062 |
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