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A New Nrf2 Inhibitor Enhances Chemotherapeutic Effects in Glioblastoma Cells Carrying p53 Mutations

SIMPLE SUMMARY: Glioblastoma (GBM) is the most common and deadliest brain tumor. Currently, there is no successful treatment available for GBM patients. Different genes are mutated in GBM tumors, including the tumor suppressor p53 gene. Another important gene responsible for cellular homeostasis is...

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Detalles Bibliográficos
Autores principales: Afjei, Rayhaneh, Sadeghipour, Negar, Kumar, Sukumar Uday, Pandrala, Mallesh, Kumar, Vineet, Malhotra, Sanjay V., Massoud, Tarik F., Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775980/
https://www.ncbi.nlm.nih.gov/pubmed/36551609
http://dx.doi.org/10.3390/cancers14246120