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Transcription Factors and ncRNAs Associated with CYP3A Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis

CYP3A4, CYP3A5, and CYP3A7, which are located in a multigene locus (CYP3A), play crucial roles in drug metabolism. To understand the highly variable hepatic expression of CYP3As, regulatory network analyses have focused on transcription factors (TFs). Since long non-coding RNAs (lncRNAs) likely cont...

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Detalles Bibliográficos
Autores principales: Huang, Huina, Zhang, Siqi, Wen, Xiaozhen, Sadee, Wolfgang, Wang, Danxin, Yang, Siyao, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9775998/
https://www.ncbi.nlm.nih.gov/pubmed/36551817
http://dx.doi.org/10.3390/biomedicines10123061