Monitoring and Regulating Intracellular GPX4 mRNA Using Gold Nanoflare Probes and Enhancing Erastin-Induced Ferroptosis

Glutathione peroxidase 4 (GPX4) plays an important effect on ferroptosis. Down-regulating the expression of GPX4 mRNA can decrease the content of GPX4. In this work, a gold nanoflare (AuNF) probe loaded with anti-sense sequences targeting for GPX4 mRNA was designed to monitor and down-regulate intra...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyan, Yang, Qiangqiang, Sui, Yanan, Yue, Qiaoli, Yan, Shuqing, Li, Chuan, Hong, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776005/
https://www.ncbi.nlm.nih.gov/pubmed/36551145
http://dx.doi.org/10.3390/bios12121178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776005/
https://www.ncbi.nlm.nih.gov/pubmed/36551145
http://dx.doi.org/10.3390/bios12121178

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