Cargando…

Monitoring and Regulating Intracellular GPX4 mRNA Using Gold Nanoflare Probes and Enhancing Erastin-Induced Ferroptosis

Glutathione peroxidase 4 (GPX4) plays an important effect on ferroptosis. Down-regulating the expression of GPX4 mRNA can decrease the content of GPX4. In this work, a gold nanoflare (AuNF) probe loaded with anti-sense sequences targeting for GPX4 mRNA was designed to monitor and down-regulate intra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaoyan, Yang, Qiangqiang, Sui, Yanan, Yue, Qiaoli, Yan, Shuqing, Li, Chuan, Hong, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776005/ https://www.ncbi.nlm.nih.gov/pubmed/36551145 http://dx.doi.org/10.3390/bios12121178

Ejemplares similares

GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma
por: Zhou, Yan, et al.
Publicado: (2022)

Monitoring Wound Healing with Topically Applied Optical NanoFlare mRNA Nanosensors
por: Hwang, Jangsun, et al.
Publicado: (2022)

Theaflavin-3,3′-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis
por: Xu, Chao, et al.
Publicado: (2022)

How erastin assassinates cells by ferroptosis revealed
por: Gan, Boyi
Publicado: (2022)

Two-Color-Based Nanoflares for Multiplexed MicroRNAs Imaging in Live Cells
por: Li, Jing, et al.
Publicado: (2018)

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis
por: Wang, Yue-Qi, et al.
Publicado: (2016)

The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy
por: Zhao, Yuechen, et al.
Publicado: (2020)

Arginine Expedites Erastin-Induced Ferroptosis through Fumarate
por: Guo, Xinxin, et al.
Publicado: (2023)

Fascin enhances the vulnerability of breast cancer to erastin-induced ferroptosis
por: Chen, Cong, et al.
Publicado: (2022)

Transferrin-based radiolabeled probe predicts the sensitivity of human renal cancer cell lines to ferroptosis inducer erastin
por: Shibata, Yuki, et al.
Publicado: (2021)

Synergistic Effect of Erastin Combined with Nutlin-3 on Vestibular Schwannoma Cells as p53 Modulates Erastin-Induced Ferroptosis Response
por: He, Weiwei, et al.
Publicado: (2022)

Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons
por: Zhang, Yan, et al.
Publicado: (2020)

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc(–)
por: Wang, Liyuan, et al.
Publicado: (2019)

Knockdown of SETD2 promotes erastin-induced ferroptosis in ccRCC
por: Xue, Wei, et al.
Publicado: (2023)

Curcumin reverses erastin-induced chondrocyte ferroptosis by upregulating Nrf2
por: Zhou, Yizhao, et al.
Publicado: (2023)

The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis
por: Yan, Renhong, et al.
Publicado: (2022)

Erastin-induced ferroptosis causes physiological and pathological changes in healthy tissues of mice
por: Zhao, Jing, et al.
Publicado: (2021)

Iron Administration Overcomes Resistance to Erastin-Mediated Ferroptosis in Ovarian Cancer Cells
por: Battaglia, Anna Martina, et al.
Publicado: (2022)

Erk1/2-Dependent HNSCC Cell Susceptibility to Erastin-Induced Ferroptosis
por: Savic, Dragana, et al.
Publicado: (2023)

Photocaged amplified FRET nanoflares: spatiotemporal controllable of mRNA-powered nanomachines for precise and sensitive microRNA imaging in live cells
por: Li, Jing, et al.
Publicado: (2021)

Erastin triggers autophagic death of breast cancer cells by increasing intracellular iron levels
por: Li, Mengxin, et al.
Publicado: (2020)

Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3
por: Shintoku, Ryosuke, et al.
Publicado: (2017)

Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells()
por: Hao, Shihui, et al.
Publicado: (2017)

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis
por: Kwon, Ok-Seon, et al.
Publicado: (2020)

Targeted exosome‐encapsulated erastin induced ferroptosis in triple negative breast cancer cells
por: Yu, Mengyu, et al.
Publicado: (2019)

Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
por: Yang, Yongfei, et al.
Publicado: (2020)

Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis
por: Hanke, Nora, et al.
Publicado: (2022)

Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis
por: Hu, Qian, et al.
Publicado: (2022)

Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line
por: Hoshino, Tomonori, et al.
Publicado: (2020)

Biochemical mechanism of erastin-induced ferroptotic cell death in neuronal cells: Role of PDI in ferroptosis
por: Hou, Ming-Jie, et al.
Publicado: (2023)

Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters
por: Li, Xing Yu, et al.
Publicado: (2020)

Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
por: Liu, Nan, et al.
Publicado: (2019)

Upregulation of Nrf2 Signalling and the Inhibition of Erastin-Induced Ferroptosis by Ferulic Acid in MIN6 Cells
por: Kose, Tugba, et al.
Publicado: (2022)

Erastin induces ferroptosis in cervical cancer cells via Nrf2/HO-1 signaling pathway
por: Wei, Xiaoning, et al.
Publicado: (2023)

Dihydroartemisinin initiates ferroptosis in glioblastoma through GPX4 inhibition
por: Yi, Renxin, et al.
Publicado: (2020)

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
por: Miao, Yu, et al.
Publicado: (2022)

Extracellular CIRP Promotes GPX4-Mediated Ferroptosis in Sepsis
por: Shimizu, Junji, et al.
Publicado: (2022)

Copper-dependent autophagic degradation of GPX4 drives ferroptosis
por: Xue, Qian, et al.
Publicado: (2023)

Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis
por: Liu, Ming, et al.
Publicado: (2021)

Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
por: Zhu, Ting, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1939s887e6c5pstdof095js04d