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GRP75 Modulates Endoplasmic Reticulum–Mitochondria Coupling and Accelerates Ca(2+)-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy

Endoplasmic reticulum (ER) and mitochondrial dysfunction play fundamental roles in the pathogenesis of diabetic retinopathy (DR). However, the interrelationship between the ER and mitochondria are poorly understood in DR. Here, we established high glucose (HG) or advanced glycosylation end products...

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Detalles Bibliográficos
Autores principales: Li, Yan, Li, Hong-Ying, Shao, Jun, Zhu, Lingpeng, Xie, Tian-Hua, Cai, Jiping, Wang, Wenjuan, Cai, Meng-Xia, Wang, Zi-Li, Yao, Yong, Wei, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776029/
https://www.ncbi.nlm.nih.gov/pubmed/36551205
http://dx.doi.org/10.3390/biom12121778