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Sialyltransferase Inhibitor Ac(5)3F(ax)Neu5Ac Reverts the Malignant Phenotype of Pancreatic Cancer Cells, and Reduces Tumor Volume and Favors T-Cell Infiltrates in Mice
SIMPLE SUMMARY: An increase of sialic acid in the cancer cells’ surface is a hallmark of tumours, including pancreatic cancer, and it has been related to tumour malignancy and immune suppression. In this work, we have assessed for the first time the potential of the sialyltransferase inhibitor, Ac(5...
Autores principales: | Miró, Laura, López, Júlia, Guerrero, Pedro E., Martínez-Bosch, Neus, Manero-Rupérez, Noemí, Moreno, Mireia, Ortiz, M. Rosa, Llop, Esther, Navarro, Pilar, Peracaula, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776040/ https://www.ncbi.nlm.nih.gov/pubmed/36551619 http://dx.doi.org/10.3390/cancers14246133 |
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