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Inactivation of Yes-Associated Protein Mediates Trophoblast Dysfunction: A New Mechanism of Pregnancy Loss Associated with Anti-Phospholipid Antibodies?

Pregnancy morbidity induced by anti-phospholipid antibodies (aPL+/PM+) is mainly thought to arise from placental abnormalities. We attempted to investigate the effect of aPL on the activity of Yes-associated protein (YAP) in the trophoblast and how YAP regulated human trophoblasts function. Thus, HT...

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Detalles Bibliográficos
Autores principales: Huang, Zengshu, Tang, Zhijing, Guan, Haiyun, Leung, Wingting, Wang, Lu, Xia, Hexia, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776042/
https://www.ncbi.nlm.nih.gov/pubmed/36552052
http://dx.doi.org/10.3390/biomedicines10123296