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Hydrogen-Rich Saline Attenuates Chronic Allodynia after Bone Fractures via Reducing Spinal CXCL1/CXCR2-Mediated Iron Accumulation in Mice

Purpose: Neuroinflammation often initiates iron overload in the pathogenesis of neurological disorders. Chemokine-driven neuroinflammation is required for central sensitization and chronic allodynia following fractures, but specific molecular modulations are elusive. This present study explored whet...

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Detalles Bibliográficos
Autores principales: Wang, Yanting, Wang, Pei, Liu, Cuicui, Chen, Wei, Wang, Pingping, Jiang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776060/
https://www.ncbi.nlm.nih.gov/pubmed/36552070
http://dx.doi.org/10.3390/brainsci12121610