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Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing
SIMPLE SUMMARY: We integrated three distinct methods (driver nodes, core module, and core nodes) to produce different HNSs for identifying hub genes involved in epithelial ovarian cancer (EOC). Immunohistochemical (IHC), qRT-PCR, and Western blotting were performed to validate the expression of hub...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776135/ https://www.ncbi.nlm.nih.gov/pubmed/36552360 http://dx.doi.org/10.3390/biology11121851 |