Identify Biomarkers and Design Effective Multi-Target Drugs in Ovarian Cancer: Hit Network-Target Sets Model Optimizing

SIMPLE SUMMARY: We integrated three distinct methods (driver nodes, core module, and core nodes) to produce different HNSs for identifying hub genes involved in epithelial ovarian cancer (EOC). Immunohistochemical (IHC), qRT-PCR, and Western blotting were performed to validate the expression of hub...

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Detalles Bibliográficos
Autores principales: Esmaeilzadeh, Amir Abbas, Kashian, Mahdis, Salman, Hayder Mahmood, Alsaffar, Marwa Fadhil, Jaber, Mustafa Musa, Soltani, Siamak, Amiri Manjili, Danial, Ilhan, Ahmet, Bahrami, Abolfazl, Kastelic, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776135/
https://www.ncbi.nlm.nih.gov/pubmed/36552360
http://dx.doi.org/10.3390/biology11121851

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