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gldc Is Essential for Renal Progenitor Patterning during Kidney Development

The glycine cleavage system (GCS) is a complex located on the mitochondrial membrane that is responsible for regulating glycine levels and contributing one-carbon units to folate metabolism. Congenital mutations in GCS components, such as glycine decarboxylase (gldc), cause an elevation in glycine l...

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Detalles Bibliográficos
Autores principales: Weaver, Nicole E., Healy, Allison, Wingert, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776136/
https://www.ncbi.nlm.nih.gov/pubmed/36551976
http://dx.doi.org/10.3390/biomedicines10123220