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Oxidative Stress-Induced HMGB1 Translocation in Myenteric Neurons Contributes to Neuropathy in Colitis

High-mobility group box 1 (HMGB1) is a damage-associated molecular pattern released by dying cells to stimulate the immune response. During cell death, HMGB1 is translocated from the nucleus to the cytoplasm and passively released. High levels of secreted HMGB1 are observed in the faeces of inflamma...

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Detalles Bibliográficos
Autores principales: Stavely, Rhian, Sahakian, Lauren, Filippone, Rhiannon T., Stojanovska, Vanesa, Bornstein, Joel C., Sakkal, Samy, Nurgali, Kulmira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776169/
https://www.ncbi.nlm.nih.gov/pubmed/36551259
http://dx.doi.org/10.3390/biom12121831